Pathology

Multi Mineral Deficiencies can lead to poor development of the malefaction structure of the face leading to small mouths and tooth overcrowding. This can result in crooked teeth and wisdom teeth needing to be removed. The deficiencies can also result in poor bone mineral density resulting in cavities because the collagenous tissues that form the structures essential for calcium deposition into the bones are no longer being maintained. Strategies taken by dentists and orthodontists like the ones outlined below can only result in further complications. Root canals may become infected years down the line and hide necrotic bone tissue below them and so can wisdom tooth cavitation's that are a result of a improper wisdom tooth extraction. Many anaerobic bacteria can begin to breed at the site and slowly spread to other parts of the body contributing to many immune and cancer related disease.

Those with multi mineral deficiencies may also suffer from osteoporosis, joint issues, skin issues, unusual weight gain or loss, memory and cognitive impairments and inability to mount an immune response to viral, bacterial or fungal threats. Since copper, zinc and vitamin C need to all be present simultaneously for the production of collagen along with intake of bioavailable protein. Deficiencies will also result in gut permeability and bacterial overgrowth in the small and large intestine. Hair mineral analysis and blood tests will easily miss deficiencies in key minerals rendering them useless. This is where detailing a comprehensive dietary history is important because correcting lifelong deficiencies will take more work since their will also be accumulation of toxins that will need to be dealt with before having a chance at correcting mineral inadequacy.

Mold & Biotoxins exposures most common in water damaged buildings, the black stuff that might be on our window sills, under our sink, crawl space, shower, toilet, basement wall, inside water damaged walls or lingering spores in our carpets. Air quality is extremely important, the humidity in our homes should be maintained between 30 and 50% preferably on the lower end. If this is not achieved or their are places in the home such as windows and roof extrusions that are improperly constructed or maintained than water damage can result. Within 24 to 48 hours of the occurrence of water damage mold can start to grow. The paper backed side of drywall panels are particularly vulnerable to this and unfortunately they can go unseen for a long time. Over half of all buildings contain mold so it is a more common problem than we realize and the complex part of this issue is that some of us can live in a water damaged building for years till we start to develop symptoms. This makes it confusing and becomes even more complex when we factor in that 25% of us have variations in the HLA set of genes that would make us additionally vulnerable to mold exposure.

Copper Deficiency can be the result of fluoride and glyphosate chelating copper from the food supply reducing its availability for complex IV of the electron transport chain resulting in a drop of ATP causing reduced energy output by the mitochondria. Copper is also required for Superoxide dismutase and Metallothionein important for managing oxidation and metal toxicity in the body. Without enough copper the diamine oxidase enzyme will also falter making is difficult for the body to degrade histamine. This all leads to multi-system failure very quickly if left unaddressed for a period of time.

Vitamin A can be found both in the form of retinol palmitate, retinol and beta-carotene in prenatal and multivitamin supplements. Under no circumstance is it advisable that a pregnant or preparing to be become pregnant women should have supplemental A. It is already found in huge quantities in plants, added to 1 and 2 % milk, added to butter, added to cereals in the US and also added to some flours in the US (plant sources are enough we should stop adding A to other foods). Vitamin A is well known for contributing to birth defects in children. It can also be a major contributing factor towards cradle cap, child eczema, immune issues, excessive spit up and irregular sleep patterns in infancy. Children have very small livers and low capacity to store A, overwhelm this and the body converts retinol to retinoic acid at a very high ratio potentially causing DNA damage. It is absurd that we continue to flood the population with vitamin A. And I think with such a reputation we should at least question the dose we are getting in addition to questioning the breadth of our exposure to this molecule. In many Atlantic regions we know COD liver oil was a big craze for a time, please do not ingest COD liver oil when pregnant or ever it is an extreme source of vitamin A.

Omega 6 Above 4% of Calories competes with Omega-3, binding to cardiolipin in mitochondria and reducing cell membrane fluidity. This can result in insulin resistance when cell membranes are in poor health. Also impairing the storage and utilization of other healthy fats, such as omega-3 fatty acids, monounsaturated fats, and saturated fats. To support optimal glucose utilization and maintain metabolic health, prioritizing insulin sensitivity and a balanced intake of quality fats is crucial, mitigating the negative effects of excessive omega-6 consumption. Historically, omega-6 fats constituted less than 5% of daily calorie intake, but today the average person consumes over 20% from these sources.

Aiming for an ideal Omega-3 to Omega-6 ratio of 1:1 ensures proper delta6-desaturase enzyme function, maintaining a surplus of Omega-3 in the body. Excessive Omega-6 fats, with multiple double bonds, are prone to lipid peroxidation, causing damage to every cell and the endothelium of blood vessels. Damaged endothelium requires repair. Omega-6 fats contribute to LDL cholesterol oxidation, prompting macrophages to recognize and engulf the oxidized particles. This initiates the cascade of atherosclerosis, heart disease, Alzheimer's, and cancer, with the initiation speed influenced by genetic factors. Cells with damaged DNA initiate apoptosis, a process triggered by CASPASE 3 signaling. Excess omega 6 blocks the ability of the cardiolipin to signal to CASPASE 3 allowing cells with DNA mutations to continue living, eventually this cell develops a mutation relating to its identity or reproduction initiating the cancering process.

Iron Dysregulation due to oral vitamin D consumption and a lack of copper and magnesium in the diet iron absorption has increased significantly in the human intestinal tract. This increase in iron and deficiency in the carrier protein cofactors mentioned above lead to excess and under-utilized iron. 

Heavy Metal exposure to elemental mercury vapor from mercury amalgam fillings is a mitochondrial poison. Large fish like mackerel, swordfish and tuna may also carry significant amounts of methyl mercury in addition to farmed fish like salmon and cod. Lead and cadmium contamination can be significant in chocolate products. Arsenic can be abundant in brown rice in fact their is 80 times more arsenic in brown rice than in white rice. Iron is also a heavy metal and can be present in large quantity's in untested well water and enter our food from cast iron pans.

Glyphosate was actually originally patented as an antibiotic before it was used as an herbicide, so most vegetables are now antibiotics of the worst kind. Once in the human digestive tract it has been found to target good bacteria and spare the life of bad bacteria making this a serious issue for our microbiome. Glyphosate is also a major chelator of copper an essential mineral of the electron transport chain in the mitochondria.

High Fructose Corn Syrup unnaturally extracted and refined from corn increase insulin at higher and more prolonged concentrations than are suitable for human biology. They can also be a source of pesticides like glyphosate. HFCS is also more difficult for the liver to metabolize than than the simpler glucose molecule.

Zero Calorie Sweeteners impair insulin signaling due to the fact that they provide sweet flavor signal without the message or gift of calories. When the body senses sweetness without the presence of real sugar it now creates confusion among the insulin. We really do not want to send insulin out into the blood with the false pretense that their will be a job for it to execute once it is there. Repeating this over and over causes insulin resistance. Our body is not an experiment, get rid of the soulless sugar. To maintain optimal health, it is essential for our muscle cells, liver cells, kidney cells, and brain cells to have the ability to readily uptake glucose when necessary. This process, known as insulin sensitivity, is highly desirable. Glucose itself is not the enemy, especially when consumed as part of its natural food matrix.

Correcting the metabolic issues caused by omega-6 imbalances improves our ability to utilize both glucose and ketones as fuel sources. By addressing this broken metabolism, we can enhance insulin sensitivity and facilitate the efficient uptake of glucose by various organ cells. It is worth noting that impaired insulin sensitivity and glucose metabolism are also associated with certain disease pathologies, including Alzheimer's disease, but further information on that topic can be found in dedicated resources related to Alzheimer's.

Plant Sterols mimic human cholesterol and can lead to the formation of crystals inside of arterial plaque being a contributor to eventual eruptions and clots in the artery. They are found concentrated in inappropriately large numbers in seed oils. They are also generally quite high in nuts and seeds. They remain somewhat elevated in olive and avocado oil while being of significant enough concentrations in nuts, seeds and whole avocados. Omega 6 seed oils also contain loads of plant sterols (phytosterols) that mimic and block absorption in the human gut and reduce the amount of healthy LDL in the bloodstream while increasing the circulation of oxidized LDL. Like sending fire trucks on fire to put out a burning building. Now, consider the consumption of saturated fat from animal foods, similar to our ancestors, but with less of the fragile double bond omega 6 fats. It is essential to put an end to the debate once and for all: there is no such thing as "bad" cholesterol. Cholesterol is produced by the body and is necessary for the proper functioning of organs. The problem arises when cholesterol or the body becomes inflamed through other pathways described earlier. This demonstrates why drugs like Crestor are not the solution and have shown limited efficacy in preventing heart attacks, as indicated by their own published studies. 

Vitamin D would have never been consumed without K2 occurring naturally in ancestrally raised ruminant animals. The reason vitamin D supplementation can be indirectly linked to kidney stones is because it increases the intestinal absorption of calcium. Without adequate K2, copper, zinc and vitamin C calcium hangs around in body in places where it should not be accumulating, in the blood, urine and arterial walls. These suggestions along with boron can help keep calcium in a metabolically active state and into the bones and teeth. Vitamin D from sunshine is recommended due to the way it interacts with vitamin A and most importantly how it is synthesized from cholesterol. Sunshine is therefore a more natural and intelligent method to manage cholesterol. That's not medical advice and you should talk to your doctor but that might allow you to consider throwing your statins in the trash. Where I believe they belong.