Aluminum
Sources and critical human enzymes that aluminum inhibits.
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Aluminum is not an essential mineral for the human body and inhibits the metabolism of other minerals and enzymes that are essential for optimal function. In relation to neurological issues it inhibits the breakdown of acetylcholine via inhibition of acetylcholinesterase. It also inhibits folate metabolism (vitamin B9) and the inhibition of cobalamin recycling (vitamin B12) this can also contribute to neurological issues like Parkinson's due to folate being a cofactor for the function of COMT and other neurotransmitter operations, so we can see it indirectly impacts the function of some enzymes while directly impacting the operation of others.
The Importance of Minerals for Liver Produced Protein Metallothionein Involved in Detoxification of Metals Including Aluminum
Copper, Zinc and Selenium are the ideal team to create more metallothionein in the liver, enhancing displacement of aluminum from bodily tissues. Molybdenum, Iodine and Boron are also essential to balance these minerals and are complimentary to their function. Its important to work with a functional medicine practitioner and consult your GP when considering supplementation for any reason. Natural food sources may not be able to cover needs for copper, iodine and boron so it can be useful to consider dosing dependent on the context of your personal situation. Since metallothionein is made in the liver any responsible metal detox protocol is going to require that we take care of our liver. Abstain from alcohol, omega 6, pain killers, high fructose corn syrup, excess fructose and anything that is known to oversaturate and damage liver cells for example fat soluble vitamin A, access our vitamin A page under the fraud section for more information about vitamin A. Since vitamins D, E and K are also fat soluble caution should also be exercised when ingesting these as supplements. Diet and sunshine should provide more than enough of these vitamins and that is also true for vitamin A. Minerals also enhance the body's ability to maintain vitamin D in the active form.
The Importance of Vitamins involved in Detoxification of Metals including Aluminum
Riboflavin (B2) is important for the recycling of Cobalamin (B12) to improve neurotransmitter function and Glutathione important for whole body detoxification. This can also be paired with Thiamine (B1) and (B3) important for cleaning up by-products of the neurotransmitter system.
While it is important to emphasize that some exposures to Aluminum may not be curable these steps may improve quality of life for those facing disease from serious occupational exposures.
Common sources of aluminum exposure per 100g:
Table salt 0.5mg
Baking Powder 0.5 to 1.5mg
Processed Cheese 1 to 2 mg
Vaccines
Pancake/Waffle/Cake mixes 0.5 to 1mg
Aluminum Cookware
Aluminum Foil
Spinach 1 to 3mg
Canned Foods
Alternatives:
Himalayan Salt / Redmond Real Salt / Potassium Chloride
Potassium Bicarbonate
Goats/ Mozzarella Cheese
Minerals for broad & robust immunity.
DIY mix
Stainless Steel Cookware
Glass Storage
Lettuce or Fruits
Whole Foods
Uncommon Sources of Exposure
The most notable exposure to aluminum would be through occupational exposure to McIntyre Powder a "treatment" developed to guard against the inhalation of silica dust in certain silica containing mines. Some antiperspirants and deodorants contain aluminum compounds. While these products are applied to the skin and not ingested, there is potential for absorption through the skin. Certain medications, including some antacids, anti-diarrheal drugs, and some buffered aspirins, may contain aluminum compounds.
Additional Effects of Aluminum on the Body
You can see four enzymes G6PD, CAT, SOD3 and SOD2 in the glutathione pathway very important for immunity, energy metabolism and detoxification. This chart is illustrated by Dr. Ben Lynch detailing the cofactors required and the antagonists of enzymes in the glutathione pathway.
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